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Table 1 Comparison of Ld-RAC/AKT-like gene with trypanosomatid and human homologues. Identity and similarity percentages of the full cDNA and protein sequences are shown as compared to the herein reported Ld-RAC/AKT-like gene from L. donovani (MHOM/IN/80/Dd8)

From: Identification of a RAC/AKT-like gene in Leishmania parasites as a putative therapeutic target in leishmaniasis

Species

cDNA % identity

Protein % identity

Protein % similarity

L. donovani (Nepal)

97.8

98.0

99.2

L. braziliensis

89.6

92.9

94.5

L. infantum

97.7

98.8

99.2

L. major

98.0

98.8

98.8

L. mexicana

96.0

96.7

97.6

L. panamensis

90.1

93.9

96.6

T. cruzi

45.6

32.5

46.3

T. vivax

41.8

32.9

48.1

T. brucei

42.0

34.6

48.4

Human AKT1

43.9

26.5

43.2

Human AKT2

42.1

26.1

41.5

Human AKT3

43.8

25.4

40.7