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Fig. 6 | Parasites & Vectors

Fig. 6

From: Stimulation of IL-1β and IL-6 through NF-κB and sonic hedgehog-dependent pathways in mouse astrocytes by excretory/secretory products of fifth-stage larval Angiostrongylus cantonensis

Fig. 6

ESP induce NF-κB expression. a Fluorescence microscopy demonstrated the expression of NF-κB in astrocytes from the hippocampus of BALB/c mice infected with 25 A. cantonensis third-stage larvae on day 28 post-infection (GFAP: green; NF-κB: red; colocalization of NF-κB and Shh: yellow). b Western blot analysis of NF-κB in astrocytes treated with ESP for 0–8 h. Data are expressed as the mean ± SD from three independent experiments (**P < 0.01). Scale-bars: 100 μm

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