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Fig. 7 | Parasites & Vectors

Fig. 7

From: Stimulation of IL-1β and IL-6 through NF-κB and sonic hedgehog-dependent pathways in mouse astrocytes by excretory/secretory products of fifth-stage larval Angiostrongylus cantonensis

Fig. 7

NF-κB induces Shh signaling pathway activation. a Western blot analysis of NF-κB, Shh, Ptch, and Smo in astrocytes co-cultured with ESP alone or JSH-23 for 2 h and then with 500 μg/ml ESP for 4 h; β-actin is shown as a control. Data are expressed as the mean ± SD from three independent experiments (**P < 0.01, ***P < 0.001). b The expression levels of Shh and GFAP in astrocytes. The Shh and GFAP protein expressions were determined by immunofluorescence staining of astrocytes with ESP alone or JSH-23 for 2 h and then with 500 μg/ml ESP for 4 h. (GFAP: green; Shh: red; DAPI: blue)

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Parasites & Vectors

ISSN: 1756-3305

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