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Fig. 3 | Parasites & Vectors

Fig. 3

From: Praziquantel treatment after Schistosoma japonicum infection maintains hepatic insulin sensitivity and improves glucose metabolism in mice

Fig. 3

Dynamic gene expression of insulin sensitivity pathway targets in the liver after PZQ or CMC treatment in Infection-Chemotherapy model mice. a mRNA transcription of glucose and insulin sensitivity pathway related genes after PZQ or CMC treatment, detected by real-time quantitative PCR. b Insulin stimulated Akt phosphorylation in livers from vehicle and PZQ treated mice examined by western blot (p-Akt: phospho-Akt; t-Akt: total Akt). Statistical comparisons are indicated as follows: * C57BL/6-inf-CMC group vs C57BL/6-con group; # C57BL/6-inf-PZQ group vs C57BL/6-con group; & C57BL/6-inf-PZQ group vs C57BL/6-inf-CMC group. *, # and & P < 0.05; **, ## and && P < 0.01

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