Skip to main content

Table 3 Mean adult heartworm counts and percentage reductions at necropsy (compared with control) after treatment with a single SC dose of either PH 6 (0.17 mg/kg) or PH 12 (0.5 mg/kg) or a single oral treatment with moxidectin (0.25 mg/kg) on Day 0

From: Microfilarial reduction following ProHeart® 6 and ProHeart® SR-12 treatment in dogs experimentally inoculated with a resistant isolate of Dirofilaria immitis

Test Group

Values

Live Adult D. immitis Counts3

Males

Females

Total

Control1

Mean

Mean

% Reduction

7.7

7.7

15.3a

PH 61

8.2

8.5

16.7a

0%

0%

0%

Control2

Mean

Mean

% Reduction

8.7

10.0

18.7a

PH 122

7.7

6.5

14.9a

5%

30%

19%

Control2

Mean

Mean

% Reduction

8.7

10.0

18.7a

Oral Moxidectin (0.25 mg/kg) 2

8.3

7.7

16.0a

4%

23%

14%

  1. 1Necropsied on Day 168
  2. 2Necropsied on Day 84
  3. 3Surgically transplanted with 10 pairs of heartworms ~12 weeks prior to treatment
  4. aMeans with the same superscripts and not statistically different (P > 0.05)