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Table 1 Live adult heartworm counts: Individual dog counts with means, percent reductions, and statistical comparisons. Dogs each inoculated with 50 L3 (JYD-34 isolate) on Day 2 and necropsied on Day 150 (148 days PI)

From: Evaluation of the efficacy of ProHeart® 6 (moxidectin) against a resistant isolate of Dirofilaria immitis (JYD-34) in dogs

Group

Animal ID

Live Adult Worm Counts

Male

Female

Total

T01

Saline Control

0 mg/kg

HUC-4

8

14

22

QQY-3

14

9

23

TEB-4

10

17

27

PED-4

12

25

37

RCB-4

14

11

25

XRQ-3

9

12

21

Arithmetic Mean:

11.2

14.7

25.8

Geometric Mean:

10.9

13.9

25.4

T02

ProHeart® 6

Single Treatment

Day 0

FHA-4

1

0

1

ZEB-4

0

0

0

YZX-3

0

0

0

YKB-4

0

0

0

RVW-3

0

0

0

PIW-3

0

0

0

Arithmetic Mean:

0.2

0.0

0.2

Geometric Mean:

0.1

0.0

0.1a

% Reduction Arithmetic Mean:

98.5

100.0

99.4

% Reduction Geometric Mean:

98.9

100.0

99.5

  1. aStatistical comparison were made on geometric means only; PH® 6 mean statistically different form the control mean (P < 0.0001)