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Table 1 Live adult heartworm counts: Individual dog counts with means, percent reductions, and statistical comparisons. Dogs each inoculated with 50 L3 (JYD-34 isolate) on Day 2 and necropsied on Day 150 (148 days PI)

From: Evaluation of the efficacy of ProHeart® 6 (moxidectin) against a resistant isolate of Dirofilaria immitis (JYD-34) in dogs

Group Animal ID Live Adult Worm Counts
Male Female Total
T01 Saline Control 0 mg/kg HUC-4 8 14 22
QQY-3 14 9 23
TEB-4 10 17 27
PED-4 12 25 37
RCB-4 14 11 25
XRQ-3 9 12 21
Arithmetic Mean: 11.2 14.7 25.8
Geometric Mean: 10.9 13.9 25.4
T02 ProHeart® 6 Single Treatment Day 0 FHA-4 1 0 1
ZEB-4 0 0 0
YZX-3 0 0 0
YKB-4 0 0 0
RVW-3 0 0 0
PIW-3 0 0 0
Arithmetic Mean: 0.2 0.0 0.2
Geometric Mean: 0.1 0.0 0.1a
% Reduction Arithmetic Mean: 98.5 100.0 99.4
% Reduction Geometric Mean: 98.9 100.0 99.5
  1. aStatistical comparison were made on geometric means only; PH® 6 mean statistically different form the control mean (P < 0.0001)