Does evaluation of in vitro microfilarial motility reflect the resistance status of Dirofilaria immitis isolates to macrocyclic lactones?

Table 2 Inhibition of microfilariae motility by ivermectin in vitro

Microfilariae of the isolates were isolated and incubated with various concentrations of ivermectin for 24 h at 37 °C in a 5% CO₂ atmosphere. Motility was assessed using the ‘Worminator’ as described and the IC₅₀ calculated using Prism 6

ISSN: 1756-3305