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Table 4 Geometric mean number of blood-fed and live mosquitoes per dog and immediate anti-feeding and knock-down efficacy (%) of DPP* after 1 h exposure (%) on Days 21 and 28 after administration in Group 2 and 4 (n = 16) dogs

From: Shifting the paradigm in Dirofilaria immitis prevention: blocking transmission from mosquitoes to dogs using repellents/insecticides and macrocyclic lactone prevention as part of a multimodal approach

 

Groups 1 and 3 (untreateda)

Groups 2 and 4 (DPPb)

Efficacy (%)

 

Mean/Total (range)

Mean/Total (range)

  

Day

Fed

Live

Fed

Live

Anti-feeding

Knock-down

21

13.1/30.4

(7–24)

28.3/30.4

(24–40)

0.0/30.7

(0–1)

2.3/30.7

(0–11)

99.7

91.8

28

11.7/23.4

(6–17)

21.5/23.4

(17–33)

0.2/23.5

(0–3)

1.8/23.5

(0–10)

98.4

91.9

Overall

    

99.0

91.8

  1. aUntreated at the time of the mosquito exposure
  2. bDPP: dinotefuran + permethrin + pyriproxyfen (Vectra® 3D) applied on Day 0