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Table 1 Samples with discordant testing results prior to heat treatment (and results following heat treatment) for the three testing platforms

From: Comparative evaluation of commercially available point-of-care heartworm antigen tests using well-characterized canine plasma samples

Samplea

HW Categoryb

Witness® HW

SNAP® RT

DiroChek®

Sample OD

(+ control OD) Initial Test

Sample OD

(+ control OD)

Post-Heat Treatment

1

BL

+ (+)

− (vol.b)

+ (+)

0.038 (0.352)

0.049 (0.309)

23

BL

+ (+)

− (+)

+ (+)

0.013 (0.363)

0.070 (0.309)

26

BL

− (−)

− (−)

+ (−)

0.015 (0.363)

0.000 (0.309)

52

BL

+ (+)

− (+)

+ (+)

0.027 (0.470)

0.124 (0.309)

62

BL

+ (+)

− (+)

+ (+)

0.020 (0.470)

0.077 (0.309)

68

BL

− (+)

− (+)

+ (+)

0.019 (0.380)

0.050 (0.309)

92

Neg.

+ (−)

− (−)

− (−)

0.000 (0.380)

0.000 (0.309)

98

BL

+ (+)

− (+)

− (+)

0.004 (0.380)

0.025 (0.309)

116

BL

− (−)

+ (−)

− (−)

0.001 (0.337)

0.000 (0.309)

121

BL

+ (+)

− (vol.c)

− (+)

0.009 (0.337)

0.126 (0.309)

  1. Sample OD values (DiroChek®) prior to and following heat treatment are included
  2. aSample number indicates the order in which samples were tested
  3. b BL borderline
  4. cInsufficient volume (<150 μL) precluded testing on all testing platforms