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Table 2 Antibacterial interpretive categories (breakpoints) for tetracycline antibacterial agents in dogs from CLSI [17]

From: Considerations for using minocycline vs doxycycline for treatment of canine heartworm disease

Drug

Susceptible

Intermediate

Resistant

Doxycycline

≤ 0.12 μg/mL

0.25 μg/mL

≥ 0.5 μg/mL

Tetracycline

≤0.25 μg/mL

0.5 μg/mL

≥1.0 μg/mL

Minocycline

≤0.5 μg/mL

1.0 μg/mL

≥2.0 μg/mL