|
Site
|
Groupa
|
Lesion Score
|
Significanceb
|
|---|
|
Bronchus
|
A
|
1.40
| |
|
B
|
1.89
|
0.010
|
|
C
|
2.40
|
0.003
|
|
Bronchiole
|
A
|
1.65
| |
|
B
|
1.89
| |
|
C
|
2.50
|
0.009
|
|
Alveolus/Smooth Muscle
|
A
|
1.40
| |
|
B
|
2.11
|
0.050
|
|
C
|
2.60
|
0.001
|
|
Arteriole
|
A
|
1.75
| |
|
B
|
2.39
|
0.002
|
|
C
|
2.70
|
0.002
|
|
Pulmonary Artery
|
A
|
1.20
| |
|
B
|
2.22
|
0.001
|
|
C
|
2.60
|
0.001
|
|
Bronchiole Lumen to Wall Ratioc
|
A
|
1.416
| |
|
B
|
1.016
|
0.001
|
|
C
|
1.080
|
0.001
|
|
Pulmonary Arteriole Lumen to Wall ratioc
|
A
|
0.332
| |
|
B
|
0.528
| |
|
C
|
1.187
|
0.001
|
-
aTreatment groups: Group A, selamectin topical; Group B, oral ivermectin initiated on Day 70 PI; Group C, infected, no treatment
-
bSignificance difference (ANOVA p > 0.05) noted between groups for each variable examined, and pairwise comparison (Holm-Sidak) significance in table notates differences between group B or C compared to group A
-
cLumen to wall ratio is morphometric measure of area of lumen compared to area of wall of at least 5 bronchioles and 5 arterioles from each cat. Group B was not significantly different from Group C for any variable
