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Table 5 Results of flea infestations at 12 h post-treatment and 12 h after weekly infestations in Study 4

From: Assessment of the speed of flea kill of lotilaner (Credelio™) throughout the month following oral administration to dogs

 

Day of infestation and flea count

0

7

14

21

28

35

Control

Arithmetic mean ± SD

89.5 ± 36.9

69.8 ± 18.0

75.1 ± 22.6

75.8 ± 22.6

76.5 ± 19.4

59.8 ± 10.1

Geometric mean

83.6

67.9

72.6

73.1

74.1

59.1

Lotilaner

Arithmetic mean ± SD

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

Efficacy (%)

100

100

100

100

100

100

Geometric mean

0.0

0.0

0.0

0.0

0.0

0.0

Efficacy (%)

100

100

100

100

100

100

Comparison

t (7) = 32.1, P < 0.0001

t (7) = 49.7, P < 0.0001

t (7) = 44.7, P < 0.0001

t (7) = 43.5, P < 0.0001

t (7) = 43.9, P < 0.0001

t (7) = 75.0, P < 0.0001

  1. Abbreviation: SD standard deviation