Table 6 Results of flea infestations at 24 h post-treatment and 24 h after weekly infestations in Study 4

Control

Arithmetic mean ± SD

87.6 ± 7.4

72.1 ± 15.6

76.1 ± 22.4

65.6 ± 14.9

66.9 ± 18.3

59.5 ± 10.3

Geometric mean

87.4

70.7

73.6

64.3

65.2

58.6

Lotilaner

Arithmetic mean ± SD

0.0 ± 0.0

0.0 ± 0.0

0.1 ± 0.4

0.1 ± 0.3

0.0 ± 0.0

0.0 ± 0.0

Efficacy (%)

100

100

99.8

99.8

100

100

Geometric mean

0.0

0.0

0.1

0.1

0.0

0.0

Efficacy (%)

100

100

99.8

99.8

100

100

t ₍₇₎ = 152.3, P < 0.0001

t ₍₇₎ = 55.8, P < 0.0001

t ₍₇₎ = 38.7, P < 0.0001

t ₍₇₎ = 35.7, P < 0.0001

t ₍₇₎ = 52.4, P < 0.0001

t ₍₇₎ = 61.3, P < 0.0001