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Table 2 Geometric (arithmetic) mean counts of Ixodes ricinus and percent efficacy of lotilaner against infestations present at the time of treatment

From: Laboratory evaluation of the speed of kill of lotilaner (Credelio™) against Ixodes ricinus ticks on dogs

Time of count post-treatment

 

Untreated control

Lotilaner

Comparison

Mean (arithmetic)

Range

Mean (arithmetic)

Range

Efficacy (%)

4 h

Before incubation

16.0 (16.6)

10–23

4.8 (9.0)

0–29

69.8 (45.9)

t (7) = 2.36, P = 0.0501

Group 1 (control) and Group 3 (lotilaner)

After incubation

15.7 (16.3)

10–23

0.4 (0.9)

0–5

97.2 (94.6)

t (7) = 9.26, P < 0.0001

8 h

Before incubation

18.0 (18.9)

10–26

0.2 (0.3)

0–2

99.2 (98.7)

t (7) = 15.43, P < 0.0001

Group 2 (control) and Group 4 (lotilaner)

After incubation

17.7 (18.6)

10–26

0.0 (0.0)

0–0

100 (100)

t (7) = 24.61, P < 0.0001