Time of count post-treatment | Untreated control | Lotilaner | Comparison | ||||
---|---|---|---|---|---|---|---|
Mean (arithmetic) | Range | Mean (arithmetic) | Range | Efficacy (%) | |||
4 h | Before incubation | 16.0 (16.6) | 10–23 | 4.8 (9.0) | 0–29 | 69.8 (45.9) | t (7) = 2.36, P = 0.0501 |
Group 1 (control) and Group 3 (lotilaner) | After incubation | 15.7 (16.3) | 10–23 | 0.4 (0.9) | 0–5 | 97.2 (94.6) | t (7) = 9.26, P < 0.0001 |
8 h | Before incubation | 18.0 (18.9) | 10–26 | 0.2 (0.3) | 0–2 | 99.2 (98.7) | t (7) = 15.43, P < 0.0001 |
Group 2 (control) and Group 4 (lotilaner) | After incubation | 17.7 (18.6) | 10–26 | 0.0 (0.0) | 0–0 | 100 (100) | t (7) = 24.61, P < 0.0001 |