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Table 2 Flea count data for each treatment group and statistical analysis of flea count reduction from baseline for each treatment group

From: A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio™) in eliminating fleas in client-owned dogs in the USA

 

Lotilaner

Afoxolaner

Day 0

Arithmetic mean ± SD

70.7 ± 75.0

62.3 ± 61.8

Rangea

10–251

10–251

Geometric mean

42.3

41.8

Day 30

Arithmetic mean ± SD

0.7 ± 2.5

2.3 ± 5.5

Range

0–20

0–25

Geometric mean

0.3

0.7

% reduction

99.3

98.3

Statistical analysis

t (105) = 35.50, P < 0.001

t (47) = 21.25, P < 0.001

Day 60

Arithmetic mean ± SD

0.1 ± 0.4

0.3 ± 1.8

Range

0–3

0–12

Geometric mean

0.0

0.1

% reduction

99.9

99.8

Statistical analysis

t (93) = 38.19, P < 0.001

t (43) = 28.10, P < 0.001

Day 90

Arithmetic mean ± SD

0.0 ± 0.0

0.1 ± 0.6

Range

0–0

0–4

Geometric mean

0.0

0.1

% reduction

100

99.8

Statistical analysis

t (173) = 37.07, P < 0.001

t (43) = 27.49, P < 0.001

  1. Abbreviation: SD standard deviation
  2. aAny count > 250 was assigned the value 251