TY - JOUR AU - Rufener, Lucien AU - Danelli, Vanessa AU - Bertrand, Daniel AU - Sager, Heinz PY - 2017 DA - 2017/11/01 TI - The novel isoxazoline ectoparasiticide lotilaner (Credelio™): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls) JO - Parasites & Vectors SP - 530 VL - 10 IS - 1 AB - The isoxazolines are a novel class of parasiticides that are potent inhibitors of γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and, to a lesser extent, of inhibitory glutamate-gated chloride channels (GluCls). Lotilaner (Credelio™), a novel representative of this chemical class, is currently evaluated for its excellent ectoparasiticide properties. SN - 1756-3305 UR - https://doi.org/10.1186/s13071-017-2470-4 DO - 10.1186/s13071-017-2470-4 ID - Rufener2017 ER -