Fig. 1From: The novel isoxazoline ectoparasiticide lotilaner (Credelio™): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls)Chemical structures of chloride channel antagonists. The star indicates the chiral center for both isoxazoline molecules. The biologically active compound lotilaner is the S-enantiomer while the R-enantiomer (AHC-2229544) is inactive. Fluralaner is a racemic mixture containing both enantiomersBack to article page