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Table 3 Summary of assessments for Babesia canis infection

From: Two randomized, controlled studies to assess the efficacy and safety of lotilaner (Credelio™) in preventing Dermacentor reticulatus transmission of Babesia canis to dogs

Test Test day Cumulative proportion positive Efficacy (%) Comparison
Control Lotilaner   
Blood smear 2 8/8 0/8 100 χ 2 (1) = 16, P = 0.0002
14 15/16 0/8 100 χ 2 (1) = 20, P < 0.0001
Study 1 28 15/23 0/8 100 χ 2 (1) = 10.11, P = 0.0024
Study 2 28 6/6 0/6 100 χ 2 (1) = 12, P = 0.0022
IFA 2 8/8 0/8 100 χ 2 (1) = 16, P = 0.0002
14 15/16 0/8 100 χ 2 (1) = 20, P < 0.0001
Study 1 28 15/23 0/8 100 χ 2 (1) = 10.11, P = 0.0024
Study 2 28 6/6 0/6 100 χ 2 (1) = 12, P = 0.0022
PCR 2 8/8 0/8 100 χ 2 (1) = 16, P = 0.0002
14 15/16 0/8 100 χ 2 (1) = 20, P < 0.0001
Study 1 28 15/23 0/8 100 χ 2 (1) = 10.11, P = 0.0024
Study 2 28 6/6 0/6 100 χ 2 (1) = 12, P = 0.0022
  1. Abbreviations: IFA immunofluorescence assay, PCR polymerase chain reaction