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Table 2 Geometric (arithmetic) mean counts of live Rhipicephalus sanguineus ticks

From: Laboratory evaluations of the immediate and sustained efficacy of lotilaner (Credelio™) against four common species of ticks affecting dogs in North America

 

Day

Untreated control

Lotilaner

Comparison

Mean

Range

Mean

Range

Geometric (arithmetic) mean efficacy (%)

 

Study 2

2

25.5 (27.6)

7–36

0.0 (0.0)

0–0

100 (100)

t (13) = 19.1, P < 0.0001

9

25.1 (26.0)

15–40

0.0 (0.0)

0–0

100 (100)

t (14) = 32.0, P < 0.0001

16

22.9 (24.5)

9–36

0.1 (0.3)

0–2

99.4 (99.0)

t (14) = 15.1, P < 0.0001

23

28.6 (29.9)

19–47

0.1 (0.1)

0–1

99.7 (99.6)

t (14) = 23.9, P < 0.0001

30

21.9 (23.4)

10–35

0.1 (0.1)

0–1

99.6 (99.5)

t (14) = 18.7, P < 0.0001

37

26.1 (28.1)

13–45

0.0 (0.0)

0–0

100 (100)

t (13) = 23.3, P < 0.0001

Study 3

2

5.2 (6.5)

2–20

0.0 (0.0)

0–0

na

na

9

14.3 (16.0)

4–27

0.1 (0.1)

0–1

99.4 (99.2)

t (7) = 12.7, P < 0.0001

16

29.5 (31.0)

14–43

0.0 (0.0)

0–0

100 (100)

t (7) = 27.8, P < 0.0001

23

26.5 (27.8)

17–42

0.0 (0.0)

0–0

100 (100)

t (7) = 29.2, P < 0.0001

30

19.6 (20.4)

12–31

0.0 (0.0)

0–0

100 (100)

t (7) = 28.4, P < 0.0001

37

14.8 (15.3)

10–25

0.0 (0.0)

0–0

100 (100)

t (7) = 31.5, P < 0.0001

Study 4

2

34.2 (35.4)

17–45

0.0 (0.0)

0–0

100 (100)

t (4) = 37, P < 0.0001

9

33.6 (34.4)

24–43

0.0 (0.0)

0–0

100 (100)

t (4) = 49.6, P < 0.0001

16

30.7 (31.4)

19–42

0.0 (0.0)

0–0

100 (100)

t (4) = 42.8, P < 0.0001

23

29.9 (30.5)

20–37

0.0 (0.0)

0–0

100 (100)

t (4) = 51.9, P < 0.0001

30

28.4 (29.5)

16–39

0.0 (0.0)

0–0

100 (100)

t (4) = 36.2, P < 0.0001

37

27.2 (28.3)

15–37

0.1 (0.1)

0–1

99.7 (99.6)

t (4) = 33.5, P < 0.0001

  1. Abbreviation: na not applicable because of insufficient infestations in control dogs