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Table 4 Geometric (arithmetic) mean counts of live Ixodes scapularis ticks

From: Laboratory evaluations of the immediate and sustained efficacy of lotilaner (Credelio™) against four common species of ticks affecting dogs in North America

  Day Untreated control Lotilaner Comparison
Mean Range Mean Range Geometric (arithmetic) mean efficacy (%)  
Study 7 2 26.3 (27.5) 20–44 0.0 (0.0) 0–0 100 (100) t (6) = 24.7, P < 0.0001
9 13.8 (15.1) 4–23 0.1 (0.1) 0–1 99.3 (99.2) t (14) = 13.4, P < 0.000
16 18.9 (19.6) 12–27 0.3 (0.5) 0–3 98.4 (97.5) t (6) = 9.8, P < 0.0001
23 27.1 (27.8) 20–38 0.0 (0.0) 0–0 100 (100) t (6) = 37.0, P < 0.0001
30 21.0 (21.3) 17–28 0.1 (0.1) 0–1 99.6 (99.4) t (14) = 28.6, P < 0.0001
37 27.0 (28.0) 14–38 0.2 (0.3) 0–1 99.3 (99.1) t (6) = 18.5, P < 0.0001
Study 8 2 18.4 (18.6) 14–24 0.0 (0.0) 0–0 100 (100) t (7) = 51.0, P < 0.0001
9 14.6 (15.0) 9–21 0.0 (0.0) 0–0 100 (100) t (7) = 30.4, P < 0.0001
16 11.8 (12.8) 7–21 0.0 (0.0) 0–0 na na
23 13.6 (13.9) 10–19 0.0 (0.0) 0–0 100 (100) t (7) = 37.9, P < 0.0001
30 10.6 (13.8) 0–20 0.0 (0.0) 0–0 100 (100) t (7) = 6.9, P = 0.0002
37 14.1 (14.3) 11–17 0.0 (0.0) 0–0 100 (100) t (7) = 55.1, P < 0.0001
  1. Abbreviation: na not applicable because of insufficient infestations in control dogs