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Table 3 Geometric (arithmetic) mean counts of live Ixodes ricinus and Rhipicephalus sanguineus ticks and dead, attached, engorged ticks in Study 1

From: Laboratory evaluations of the immediate and sustained effectiveness of lotilaner (Credelio™) against three common species of ticks affecting dogs in Europe

Tick species Day Untreated control Lotilaner Comparison
Mean Range Mean Range Efficacy (%)  
Ixodes ricinus 2 18.3 (18.6) 14–26 0.7 (1.0) 0–2a 96.0 (94.6) t (14) = 11.1, P < 0.0001
9 24.5 (24.8) 20–28 0.6 (0.8) 0–2 97.7 (97.0) t (14) = 15.1, P < 0.0001
16 22.9 (23.6) 13–32 0.5 (0.8) 0–3 97.9 (96.8) t (14) = 12.3, P < 0.0001
23 23.6 (25.1) 11–33 0.6 (0.9) 0–2 97.3 (96.5) t (14) = 11.3, P < 0.0001
30 24.0 (24.6) 16–35 1.2 (1.6) 0–4 95.1 (93.4) t (14) = 9.4, P < 0.0001
37 24.2 (25.1) 12–35 0.7 (1.0) 0–3 97.1 (96.0) t (14) = 11.2, P < 0.0001
Rhipicephalus sanguineus 2 25.0 (26.8) 9–40 0.1 (0.3) 0–2b 99.4 (99.1) t (14) = 15.2, P < 0.0001
9 29.7 (30.5) 18–39 0.0 (0.0) 0–0 100 (100) t (14) = 37.6, P < 0.0001
16 27.4 (28.6) 15–37 0.0 (0.0) 0–0 100 (100) t (14) = 28.7, P < 0.0001
23 31.4 (32.3) 21–48 0.0 (0.0) 0–0 100 (100) t (14) = 40.8, P < 0.0001
30 31.8 (32.6) 19–43 0.1 (0.1) 0–1 99.7 (99.6) t (14) = 27.6, P < 0.0001
37 29.8 (30.8) 17–41 0.1 (0.1) 0–1 99.7 (99.6) t (14) = 25.4, P < 0.0001
  1. a48 h post-treatment live or dead engorged ticks were found on a single; this dog had two dead, engorged R. sanguinueus
  2. b48 h post-treatment four dogs were infested, each with two dead engorged I ricinus