Table 1 Gene expression changes in IECs treated with A. ceylanicum iL3. Using RNA-Seq, gene expression was analyzed in HT-29-MTX cells treated with A. ceylanicum larvae and compared to controls (buffer treatment)
NCBI entrez gene ID | NCBI entrez gene ID | HT-29-MTX FPKM | HT-29-MTXÂ +Â A. ceylanicum FPKM | Fold change | Reference |
|---|---|---|---|---|---|
DEFB1 (defensin beta 1) | 1672 | 9 | 3 | -1.5 | [41] |
SUCNR1 (succinate receptor 1) | 56670 | 4 | 2 | -1.1 | [42] |
IFI44 (interferon-induced protein 44) | 10561 | 2 | 4 | 1.0 | [43] |
LOC100190986 (uncharacterized) | 100190986 | 3 | 7 | 1.0 | Â |
PLK2 (polo-like kinase 2) | 10769 | 46 | 24 | -0.9 | [44] |
NEAT1 (nuclear paraspeckle assembly transcript 1) | 283131 | 115 | 210 | 0.9 | [45] |
ARL14 (ADP ribosylation factor like GTPase 14) | 80117 | 22 | 12 | -0.9 | Â |
PFKFB3 (6-phosphofructo-2-kinase/fuctose-2,6-biphosphatase 3) | 5209 | 16 | 28 | 0.8 | [46] |
APCDD1L (APC down-regulated 1 like) | 154284 | 5 | 3 | -0.8 | Â |
ADRA2A (adrenoceptor alpha 2A) | 150 | 4 | 3 | -0.7 | Â |
ADM (adrenomedullin) | 133 | 71 | 116 | 0.7 | [47] |
DUSP6 (dual specificity phosphatase 6) | 1848 | 13 | 8 | -0.7 | [48] |
ATF3 (activating transcription factor 3) | 467 | 19 | 29 | 0.7 | [49] |
LFNG (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase) | 16858 | 37 | 24 | -0.6 | [50] |
HES6 (hes family bHLH transcription factor 6) | 55502 | 37 | 24 | -0.6 | Â |
EPHB3 (Eph receptor B3) | 2049 | 8 | 5 | -0.6 | [51] |
DDX60 (DexD/H-box helicase 60) | 55601 | 0 | 1 | 1.9 | [52] |
NLRC5 (NLR family CARD domain containing 5) | 84166 | 1 | 1 | 0.9 | [53] |
TACSTD2 (tumor-associated calcium signal transducer 2) | 4070 | 35 | 52 | 0.6 | [54] |