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Fig. 2 | Parasites & Vectors

Fig. 2

From: The RIO protein kinase-encoding gene Sj-riok-2 is involved in key reproductive processes in Schistosoma japonicum

Fig. 2

Alignment of the inferred amino acid sequences of Schistosoma japonicum Sj-RIOK-2 with RIOK-2 orthologs of eight other species. The eight selected species are Schistosoma mansoni (CCD79377.1, Sm-RIOK-2), Caenorhabditis elegans (CAC70109.2, Ce-RIOK-2), Homo sapiens (NP_060813.2, Hs-RIOK-2), Xenopus tropicalis (NP_001016682.1, Xr-RIOK-2), Danio rerio (NP_998719.2, Dr.-RIOK-2), Drosophila melanogaster (NP_651365.1, Dm-RIOK-2), Saccharomyces cerevisiae (CAC70109.2, Sc-RIOK-2), Arabidopsis thaliana (AEE78772.1, At-RIOK-2). Functional domains including the wHTH region (grey), ATP binding motif (red), flexible loop (yellow), hinge region (blue), active site (green), metal binding motif (orange) are highlighted and labeled below the alignment. Red arrows indicate conserved residues within the wHTH domain and “Asp” and “Asn” residues responsible for phosphoryl transfer exits within the active site, and “Asp” required for the positioning of metal ions exits within the metal binding motif. Asterisks under the alignment indicate identical residues. “:” represents strong similarity, “.” represents weak similarity, and a lack of a symbol indicates no similarity among residues

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