Table 2 In vitro praziquantel-susceptibility of individual S.mansoni miracidia isolated from 5 children in the Lake Victoria region of Tanzania in July 2010, as measured by five minute exposure to 1 × 10−6 M PZQ and classified microscopically by shape as normal (indicating reduced susceptibility to PZQ) or tadpole shape (sensitive to PZQ)
School | Child ID | PTa | Individual infection intensity (epg) | Total no. of miracidia tested (n) | No. of less susceptible miracidia (shape normal) | No. of susceptible miracidia (shape tadpole) | Percentage of less susceptible miracidia (95% CI) |
|---|---|---|---|---|---|---|---|
Bukindo | 1026 | + | 400 | 64 | 6 | 58 | 9 (2.0–16.0) |
Kisorya | 0012 | – | 1216 | 36 | 1 | 35 | 3 (0–8.6) |
0017 | – | 2520 | 41 | 2 | 39 | 5 (0–11.7) | |
1002 | + | 330 | 45 | 4 | 42 | 7 (0–14.5) | |
1010 | + | 768 | 48 | 2 | 46 | 4 (0–9.5) | |
Total | – | – | 234 | 15 | 220 | 5.6 (3.0–9.0) |