Fig. 3

Light micrographs of ibex non-dermal organs. a Liver. Perivascular amyloid deposits in portal spaces and hepatic sinusoids (arrowheads) and congestion. b Kidney. Loss of glomerular structure due to the presence of amyloid deposits (arrowheads) at the mesangial level with a reduction of urinary spaces (amyloid nephrosis) and at the level of cortical tubular interstitium with decreased capillary lumens (chronic interstitial nephritis and ischemic tubular atrophy). c Spleen. Amyloid deposits (arrowhead) at the level of the mantle and crown of the Malpigian follicles and peri-arteriolar lymphoid sheaths of the white pulp, extending to splenic cords and venous sinuses of the red pulp (“Sago spleen”).d Adrenal gland. Loss of adrenal structure due to the presence of amyloid deposits (arrowhead) at the glomerular and fascicular levels of the adrenal cortex. Scale-bars: a, 62.7 μm; b, 62.7 μm; c, 251 μm; d, 251 μm