Fig. 4From: Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugsExpression levels of cytoskeleton related gene families. Boxplot showing the expression levels for mRNAs coding for α-tubulins (a), β-tubulins (b), kinesins (c) and dyneins (d) in each sample. Samples were compared using a two-sided Student’s t-test in R. For α-tubulins CA vs RU: t(30) = -3.586, P < 0.001; CA vs CE: t(33) = -2.148, P = 0.039; RU vs CE: t(35) = 1.515, P = 0.139. For β-tubulins CA vs RU: t(15) = -2.529, P = 0.023; CA vs CE: t(16) = -1.372, P = 0.189; RU vs CE: t(16) = 1.162, P = 0.262. For kinesins CA vs RU: t(64) = -5.092, P < 0.001; CA vs CE: t(67) = -3.522, P < 0.001; RU vs CE: t(73) = 1.608, P = 0.112. For dyneins CA vs RU: t(347) = -2.473, P = 0.014; CA vs CE: t(343) = -0.207, P = 0.836; RU vs CE: t(337) = 2.407, P = 0.017. Significant comparisons are marked with asterisks (*P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001). Abbreviations: CA, Cajamarca; RU, Rubino; CE, Cenapa; ns, not significantBack to article page