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Fig. 4 | Parasites & Vectors

Fig. 4

From: Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugs

Fig. 4

Expression levels of cytoskeleton related gene families. Boxplot showing the expression levels for mRNAs coding for α-tubulins (a), β-tubulins (b), kinesins (c) and dyneins (d) in each sample. Samples were compared using a two-sided Student’s t-test in R. For α-tubulins CA vs RU: t(30) = -3.586, P < 0.001; CA vs CE: t(33) = -2.148, P = 0.039; RU vs CE: t(35) = 1.515, P = 0.139. For β-tubulins CA vs RU: t(15) = -2.529, P = 0.023; CA vs CE: t(16) = -1.372, P = 0.189; RU vs CE: t(16) = 1.162, P = 0.262. For kinesins CA vs RU: t(64) = -5.092, P < 0.001; CA vs CE: t(67) = -3.522, P < 0.001; RU vs CE: t(73) = 1.608, P = 0.112. For dyneins CA vs RU: t(347) = -2.473, P = 0.014; CA vs CE: t(343) = -0.207, P = 0.836; RU vs CE: t(337) = 2.407, P = 0.017. Significant comparisons are marked with asterisks (*P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001). Abbreviations: CA, Cajamarca; RU, Rubino; CE, Cenapa; ns, not significant

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