| |
No. of studies
|
No. of HIV-infected patients
|
No. of patients with Isospora co-infection
|
Prevalence of Isospora co-infection (95% CI) (%)
|
Heterogeneity
|
Univariate meta-regression
|
|---|
|
P-value
|
I2 (%)
|
Coefficient (95% CI) (%)
|
P-value
|
|---|
|
Region
| | | | | | |
0.21 (-0.07–0.49)
|
0.143
|
|
Western and central Europe and North America
|
6
|
97,721
|
324
|
0.5 (0.2–0.8)
|
< 0.0001
|
92.8
| | |
|
Sub-Saharan Africa
|
21
|
3995
|
232
|
6.1 (4.5–7.7)
|
< 0.0001
|
87.0
| | |
|
Asia and the Pacific
|
24
|
2848
|
215
|
7.1 (5.2–9.0)
|
< 0.0001
|
83.4
| | |
|
Latin America and the Caribbean
|
5
|
922
|
13
|
1.0 (0.3–1.7)
|
0.349
|
10.1
| | |
|
Middle East and North Africa
|
2
|
436
|
4
|
0.8 (0.0–2.0)
|
0.279
|
14.7
| | |
|
Income level
| | | | | | |
-0.04 (-0.38–0.30)
|
0.806
|
|
Low income
|
12
|
2230
|
93
|
3.8 (2.2–5.5)
|
< 0.0001
|
91.9
| | |
|
Middle income
|
39
|
5904
|
366
|
5.8 (4.7–7.0)
|
< 0.0001
|
86.9
| | |
|
High income
|
7
|
97,788
|
329
|
0.5 (0.2–0.9)
|
< 0.0001
|
80.0
| | |
|
Patients with diarrhea
| | | | |
< 0.0001
| |
-0.43 (-0.72– -0.13)
|
0.005
|
|
Yes
|
15
|
1271
|
112
|
8.3 (5.7–10.9)
|
< 0.0001
|
66.1
| | |
|
Mixed
|
43
|
104,651
|
676
|
2.0 (1.6–2.4)
|
< 0.0001
|
90.4
| | |
|
Total
|
58
|
105,922
|
788
|
2.5 (2.1–2.9)
|
< 0.0001
|
89.8
| | |
- Abbreviations: Yes, patients with diarrhea; Mixed, including patients with or without diarrhea
