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Table 4 The effect of community mass treatment with azithromycin on associations between disease severity and C. trachomatis bacterial load in individuals with ocular C. trachomatis infection

From: The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve trachoma-endemic island communities in West Africa

  

Baseline (n = 184)

Follow-up (n = 34)

Clinical phenotype

n

ORadj (95% CI)

P-value

n

ORadj (95% CI)

P-value

F-score

 

F0

89

 

11

 
 

F1

22

1.67 (0.48–5.78)

0.417

5

2.15 (0.29–15.72)

0.450

 

F2

27

1.84 (0.60–5.68)

0.287

6

3.56 (0.24–52.19)

0.354

 

F3

42

6.16 (1.97–19.26)

0.002

9

17.71 (2.65–118.47)

0.003

P-score

 

P0

48

 

10

 
 

P1

68

6.15 (2.47–15.31)

< 0.001

13

1.25 (0.31–4.97)

0.753

 

P2

45

21.74 (6.82–69.32)

< 0.001

3

1.16 (0.18–7.62)

0.875

 

P3

24

27.61 (6.81–111.80)

< 0.001

5

11.65 (1.89–71.76)

0.008

  1. Note: Age-adjusted multivariable mixed effects linear regression analysis of loge-transformed C. trachomatis load (omcB copies/swab) accounting for household clustering and C. trachomatis infection status at baseline (OR 0.98, 95% CI: 0.25–3.86, P = 0.975). F- and P-scores were assigned using the modified FPC grading system [5]. Individuals may appear in multiple clinical grading categories. P-value is for the Wald Chi2