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Fig. 7 | Parasites & Vectors

Fig. 7

From: Enhanced expressions of neurodegeneration-associated factors, UPS impairment, and excess Aβ accumulation in the hippocampus of mice with persistent cerebral toxocariasis

Fig. 7

Impairment of the ubiquitin-proteasome system (UPS) was enhanced in the hippocampus of Toxocara canis-infected mice inoculated with low-, medium- and high-dose infections at 8, 16 and 20 weeks post-infection (wpi). a Ubiquitin accumulation in the mice hippocampus as analyzed by Western blotting. b Quantification of ubiquitin accumulation in hippocampal regions of mice given low-, medium- and high-dose infections. Data are presented as the mean with SD. *P < 0.05, **P < 0.01 and ***P < 0.001 indicate a significant difference with uninfected control mice at 10 days post-infection (dpi) and 20 wpi. Abbreviation: NS: no significant difference between 10 dpi- and 20 wpi-uninfected control mice

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