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Table 3 Relationships between the severity of canine infection with Leishmania infantum and the anti-saliva antibody response, measured at the time of sampling, approximately 2 months before patent infection, and against transmission intensity (log incidence)

From: Antibody response to sand fly saliva is a marker of transmission intensity but not disease progression in dogs naturally infected with Leishmania infantum

Severity measure n (samples) n (dogs) LRT χ2 P
Anti-saliva IgG at time of sampling
 Anti-Leishmania IgG 206 58 7.11 0.0077
 Parasites (bone marrow) 122 53 0.00 0.95
 Parasites (ear skin) 80 40 0.03 0.86
 Clinical score 195 58 0.00 0.97
Anti-saliva IgG prior to infection
 Anti-Leishmania IgG 374 58 2.79 0.095
 Parasites (bone marrow) 214 55 0.00 0.97
 Parasites (ear skin) 152 47 1.09 0.30
 Clinical score 361 58 0.02 0.90
Transmission intensity (log incidence)
 Anti-Leishmania IgG 458 94 0.00 0.96
 Parasites (bone marrow) 264 81 0.05 0.82
 Parasites (ear skin) 184 63 1.51 0.22
 Clinical score 439 92 1.04 0.31