Fig. 1From: Histopathological and immunohistochemical characterisation of hepatic granulomas in Leishmania donovani-infected BALB/c mice: a time-course studya H&E-stained liver section 15 dpi (400×). Kupffer cell harbouring a high amount of amastigotes (arrowhead). Immature granulomas formed by fused macrophages harbouring few amastigotes (arrows). Well-formed mature granuloma with a complete cellular infiltrate (*). b H&E-stained liver section 35 dpi (400×). Mature functional granuloma with few fused macrophages harbouring very few amastigotes (*). Clear granuloma without amastigotes and with presence of collagen deposition (arrow). c H&E-stained liver section 63 dpi (400×). Clear granuloma composed mainly of lymphocytes (arrow). d Immunohistochemical detection of Leishmania donovani antigens (400×). Immature granulomas harbouring a high amount of amastigotes (arrows) and mature granulomas with fewer number of amastigotes (*). Scale-bars: 100 μmBack to article page