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Fig. 1 | Parasites & Vectors

Fig. 1

From: Efficacy of ursolic acid against Echinococcus granulosus in vitro and in a murine infection model

Fig. 1

The effect of UA on E. granulosus protoscoleces cultured in vitro and related ultrastructural changes. a The viability of protoscoleces cultured in vitro with UA for 3 days was determined using the methylene blue exclusion method. The percentage of dead protoscoleces in the 0.5% DMSO control was 6.43 ± 1.00%; b-e Protoscoleces treated with 0.5% DMSO in vitro; f-i Protoscoleces cultured in vitro with UA at 40 μg/ml for 3 days. b, f Protoscoleces observed under light microscopy. c, g Stained protoscoleces observed under light microscopy. d, h The ultrastructure of the soma tegument of protoscoleces. e, i The ultrastructure of the rostellar tegument of protoscoleces. Abbreviations: g, glycocalyx; be, blunt elevation; dc, distal cytoplasm; mb, muscle bundles; gc, glycogen; v, vacuoles; l, lipid granules

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