Skip to main content

Table 2 Effects of UA on mice infected with E. granulosus for 8 months (n = 8)

From: Efficacy of ursolic acid against Echinococcus granulosus in vitro and in a murine infection model

Group

Dose (×  28 days)

Mean cyst weight ± SD (g)

Mouse deaths during the experimental period

Cyst weight reduction (%)

Control (1% tragacanth)

0.1 ml/10 g/day

19.73 ± 17.22

2

–

Mebendazole

25 mg/kg/day

7.33 ± 3.67*

1

62.9

Ursolic acid

200 mg/kg/day

11.94 ± 5.69*

1

39.5

100 mg/kg/day

12.18 ± 8.64*

0

38.3

  1. *Indicates that there were significant reductions in parasite weight achieved by treatment with mebendazole at 25 mg/kg and UA at 200 mg/kg and 100 mg/kg compared that achieved by treatment with 1% tragacanth
  2. Abbreviation: SD, standard deviation
Back to article page

Parasites & Vectors

ISSN: 1756-3305

Contact us