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Table 2 Effects of UA on mice infected with E. granulosus for 8 months (n = 8)

From: Efficacy of ursolic acid against Echinococcus granulosus in vitro and in a murine infection model

Group Dose (×  28 days) Mean cyst weight ± SD (g) Mouse deaths during the experimental period Cyst weight reduction (%)
Control (1% tragacanth) 0.1 ml/10 g/day 19.73 ± 17.22 2
Mebendazole 25 mg/kg/day 7.33 ± 3.67* 1 62.9
Ursolic acid 200 mg/kg/day 11.94 ± 5.69* 1 39.5
100 mg/kg/day 12.18 ± 8.64* 0 38.3
  1. *Indicates that there were significant reductions in parasite weight achieved by treatment with mebendazole at 25 mg/kg and UA at 200 mg/kg and 100 mg/kg compared that achieved by treatment with 1% tragacanth
  2. Abbreviation: SD, standard deviation