Skip to main content

Advertisement

Table 2 Estimates of populations living in areas endemic for three major filariases in Africa, which may be targeted with tailored mass drug administration (MDA) schemes according to the level of co-endemicity of the filarial nematode species

From: Identifying co-endemic areas for major filarial infections in sub-Saharan Africa: seeking synergies and preventing severe adverse events during mass drug administration campaigns

  Estimates of populations living in areas potentially targetable with different MDA schemes
IVM + ALB IVM IVM + ALB (E)a IVM (E)a ALB(2/year) + ITNa IVM + ALB + ITN (E + MM)a DEC + ALB + IVMb IVM (E + MM)a
Eastern Africa 8,413,869 20,963,598 45,192,922
Burundi 1,390,645
Eritrea 104,459
Ethiopia 2,340,296 14,392,313 1,161,307
Kenya 1,045,022
Madagascar 13,557,237
Malawi 2,048,395
Mozambique 493,510 742,771 10,369,358
Rwanda 38,195
Uganda 1,426,558 2,174,834 992,624
Tanzania 4,153,505 176,445 10,262,625
Zambia 6,426,817
Zimbabwe 1,273,473
Middle Africa 17,259,697 18,580,670 7,040,636 2,498,132 1,381,558 6,636,062 4,154,028 1,741,016
Angola 225,104 5,670,871 111,473 323 2314 116,774 244,993
Cameroon 3,064,962 435,486 1,270,793 245,554 331,363 1,548,497 635,665 251,586
CAR 555,240 5358 681,391 3062 697,014 756,080 60,605 33,118
Chad 1,139,547 857,065 476,212 25,770 211,614 363,059
Congo 37,729 3026 101,911 5767 39,154 29,242 27,589 9924
DRC 12,237,115 11,608,864 4,483,037 2,104,428 222,533 3744,58 2,950,335 1,038,597
Equatorial Guinea 27,293 91,172 343,735
Gabon 2078 162,798
Northern Africa 3,045,672 3,046,221 509,869 18,858 19,263 208,310 4,688,564 8669
South Sudan 2,998,136 2,969,800 509,869 18,858 19,263 208,310 843,150 8669
Sudan 47,536 76,421 3,845,414
Western Africa 50,942,788 23,619,598 3,563,101 724,325 21,278 26,738,452 72,050
Benin 1,821,021 1,847,795 97,670
Burkina Faso 4,332,528 5,527,801
Ghana 307,396 2,030,355 84,886
Guinea 3,390,416 227,213 1,461,344
Guinea-Bissau 176,095 524,123
Liberia 42,021 1,964,905
Mali 5,959,767 6758 2,861,263
Mauritania 700,830
Niger 78,987 842,637 4,837,755
Nigeria 25,275,083 10,052,102 3,563,101 724,325 21,278 7,974,187 72,050
Senegal 412,921 2,883,203
Sierra Leone 2,688,260 683,589
Togo 2,670,471
Côte d’Ivoire 6,458,292 414,466 2,664,695
Grand total 79,662,026 66,210,087 11,113,605 3,241,315 1,400,822 6,865,650 80,773,966 1,821,736
  1. aTest & Treat (measure Loiasis microfilaraemia load before treatment and exclude those with > 30,000 mf/ml)
  2. bTriple therapy with DEC is not yet recommended in countries where onchocerciasis is endemic. Re-evaluation of current endemicity is now considered in areas that were classified as hypoendemic by REMO mapping
  3. Abbreviations: ALB albendazole, CAR Central African Republic, DEC diethylcarbamazine, DRC Democratic Republic of Congo, E enhanced post-treatment monitoring for rapid determination of potential loiasis-related SAEs, IVM ivermectin, ITN insecticide-treated nets, MDA mass drug administration, MM medical monitoring at the community during 3–4 days after MDA; SAE severe adverse even