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Table 2 Geometric (arithmetic ± standard deviation) mean Ornithonyssus sylviarum mite vent counts in untreated control and in hens receiving fluralaner on Days 0 and 7

From: Efficacy and safety assessment of a water-soluble formulation of fluralaner for treatment of natural Ornithonyssus sylviarum infestations in laying hens

Day Fluralaner (mg/kg)
Control 0.25 0.5 1.0
-9 41.5 (45.4 ± 18.4) 42.6 (49.9 ± 30.4) 44.0 (50.9 ± 27.7) 38.9 (52.4 ± 61.3)
1 32.9a (41.9 ± 41.9) 12.0b (13.8 ± 7.8) 12.8b (15.1 ± 8.5) 12.4b (13.6 ± 5.9)
2 25.2c (81.8 ± 230.3) 4.3d (4.9 ± 3.2) 3.1d (4.0 ± 3.3) 4.3d (6.7 ± 6.6)
6 24.9a (37.3 ± 32.3) 0.8b (1.7 ± 3.2) 0.6b (1.1 ± 1.7) 0.5b (0.9 ± 1.7)
8 33.9a (49.2 ± 41.0) 0.2b (0.5 ± 1.5) 0.1b (0.1 ± 0.5) 0.3b (1.1 ± 3.7)
12 25.7a (49.5 ± 83.5) 0.1b (0.4 ± 1.7) 0.2b (0.8 ± 2.5) 0.3b (2.1 ± 8.2)
15 40.4a (47.6 ± 26.3) 0.4b (1.0 ± 2.8) 0.7b (1.4 ± 2.9) 0.4b (0.8 ± 1.6)
19 50.7a (56.8 ± 29.1) 4.7b,e,g (8.1 ± 8.1) 1.9b,f,k (3.6 ± 4.6) 0.4b,h,m (1.0 ± 2.4)
22 34.6c (41.6 ± 25.4) 9.4d,e (10.4 ± 5.7) 3.0d (7.5 ± 12.1) 1.9d,f (4.1 ± 6.9)
26 27.5 (34.8 ± 22.7) 29.3 (40.4 ± 26.4) 8.2 (17.7 ± 22.6) 11.8 (14.2 ± 9.2)
  1. Numbers within rows with a superscript are significantly different: treated group comparison with control: a,bP < 0.0001; c,dP < 0.05; Comparison between fluralaner groups: e,fP < 0.05; g,hP < 0.0001; k,mP = 0.014. There were no significant differences between any groups on Days -9 and 26