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Table 1 Differentially expressed (DE) genes in each group comparison, separated according to the direction and magnitude of change

From: Conjunctival transcriptome profiling of Solomon Islanders with active trachoma in the absence of Chlamydia trachomatis infection

  Comparison DI vs D (n = 2368) DI vs N (n = 6371) D vs N (n = 1933)
Upregulated genes n (%) 1388 (58.6) 2777 (43.6) 700 (36.2)
log2FC, mean (min-max) 0.378 (0.067–2.971) 0.437 (0.072–2.694) 0.322 (0.064–1.477)
Downregulated genes n (%) 980 (41.4) 3594 (56.4) 1233 (63.8)
log2FC, mean (min-max) −0.346 (− 3.686– −0.065) −0.294 (− 3.901– −0.054) −0.230 (−1.436– −0.054)