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Table 1 Differentially expressed (DE) genes in each group comparison, separated according to the direction and magnitude of change

From: Conjunctival transcriptome profiling of Solomon Islanders with active trachoma in the absence of Chlamydia trachomatis infection

 

Comparison

DI vs D (n = 2368)

DI vs N (n = 6371)

D vs N (n = 1933)

Upregulated genes

n (%)

1388 (58.6)

2777 (43.6)

700 (36.2)

log2FC, mean (min-max)

0.378 (0.067–2.971)

0.437 (0.072–2.694)

0.322 (0.064–1.477)

Downregulated genes

n (%)

980 (41.4)

3594 (56.4)

1233 (63.8)

log2FC, mean (min-max)

−0.346 (− 3.686– −0.065)

−0.294 (− 3.901– −0.054)

−0.230 (−1.436– −0.054)