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Table 1 Adult heartworm status as compared to necropsy adult heartworm recovery. Serum samples were collected immediately prior to euthanasia on study days 278–282 (10 months post-treatment). Heartworm antigen concentration was tested utilizing the DiroCHEK® heartworm antigen test kit. Heartworm antigen status was determined according to color change as recommended by the manufacturer’s recommendations. All heartworm antigen testing performed immediately prior to euthanasia accurately diagnosed live heartworm infection status. Heartworm antigen status recorded represents both pre- and post-heat-treated antigen results

From: Evaluation of heat-treating heartworm-positive canine serum samples during treatment with Advantage Multi® for Dogs and doxycycline

Group

Dog ID

Heartworm antigen status

Adult heartworm recovery

Control

43493

Positive

10

43491

Positive

10

43486

Positive

11

43481

Positive

11

43492

Positive

10

43480

Positive

12

43489

Positive

10

43484

Positive

11

IMD + MOX and doxycycline

43483

Positive

2

43485

Positive

1

43495

Positive

2

43494

Negative

0

43382a

Negative

0

43490a

Negative

0

43488

Negative

0

43487a

Negative

0

  1. aStudy animal’s serum sample converted from heartworm negative to positive post-heat-treatment at some point during this study treatment timeline