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Table 1 Diagnostic comparison of FTD vaginal swab PCR to Amplicor CT/NG and in-house ddPCR

From: Evaluation of a Chlamydia trachomatis-specific, commercial, real-time PCR for use with ocular swabs

  FTD vaginal swab PCR versus
Amplicor CT/NG (Roche) In-house ddPCR (Bio-Rad QX100)
Sensitivity 95.71 (91.74–99.68) 97.18 (93.94–100.0)
Specificity 90.00 (84.12–95.88) 96.55 (92.97–100.0)
PPV 95.71 (91.74–99.68) 98.57 (96.24–100.0)
NPV 90.00 (84.12–95.88) 93.33 (88.44–98.22)
Cohens Kappa 0.86 0.93
  1. Note: The 95% confidence intervals are shown in brackets
  2. Abbreviations: ddPCR droplet digital PCR, NPV negative predictive value, PPV positive predictive value