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Fig. 7 | Parasites & Vectors

Fig. 7

From: Microarray analysis of long non-coding RNA expression profiles uncovers a Toxoplasma-induced negative regulation of host immune signaling

Fig. 7

NONHSAT022487 mediates the secretion of cytokines in T. gondii-infected macrophages cells. The secretion of the cytokines IL-12, TNF-α, IL-1β and IFN-γ in the supernatant of various THP-1-derived macrophage cells from before (uninfected) or after T. gondii infection (T. gondii) were assessed by ELISA. Cells were transfected with shRNA-NONHSAT022487 lentiviral plasmid (sh-NONHSAT022487), shRNA control plasmid (sh-Control), pcDNA3.1-NONHSAT022487 plasmid (pc-NONHSAT022487) or pcDNA3.1 control plasmid (pc-Control) as indicated. Data are the mean with standard deviations (SD) from three independent biological replicates. *P < 0.05, **P < 0.01

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Parasites & Vectors

ISSN: 1756-3305

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