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Table 2 Changes in lymphocyte counts and cytokine levels measured in each group during the study, expressed as mean ± standard deviation (ANCOVA)

From: Prevention of disease progression in Leishmania infantum-infected dogs with dietary nucleotides and active hexose correlated compound

Parameter Supplement group Placebo group P-value supplement vs placebo (ANCOVA)
CD4+: %
 0 days 17.69 ± 15.37 13.94 ± 11.62
 60 days 19.45 ± 15.14 14.69 ± 12.40 0.752
 180 days 23.57 ± 12.45 19.89 ± 11.12 0.861
 365 days 26.33 ± 9.95 24.07 ± 9.53 0.643
CD8+: %
 0 days 12.60 ± 13.48 7.65 ± 8.63
 60 days 11.65 ± 10.40 8.16 ± 9.04 0.981
 180 days 13.72 ± 12.39 7.76 ± 5.38 0.578
 365 days 12.44 ± 6.76 10.76 ± 6.33 0.546
CD4+/CD8+ ratio
 0 days 2.01 ± 1.39 2.80 ± 1.90
 60 days 2.41 ± 2.12 2.31 ± 1.33 0.394
 180 days 3.10 ± 3.15 2.92 ± 1.50 0.238
 365 days 3.21 ± 3.43 2.75 ± 1.11 0.721
IL-6: pg/ml
 0 days 382.91 ± 940.53 269.95 ± 1054.1
 60 days 138.65 ± 371.02 393.12 ± 1424.6 0.165
 180 days 192.38 ± 456.17 118.67 ± 184.77 0.728
 365 days 314.92 ± 1024.5 34.63 ± 55.48 0.612
IL-10: pg/ml
 0 days 22.69 ± 76.01 17.92 ± 63.47
 60 days 7.52 ± 12.67 38.51 ± 147.25 0.208
 180 days 4.33 ± 4.34 69.35 ± 231.80 0.172
 365 days 6.53 ± 10.01 2.68 ± 0.74 0.282
TNF-α: pg/ml
 0 days 123.14 ± 292.94 81.58 ± 308.77
 60 days 40.47 ± 95.60 112.17 ± 397.27 0.150
 180 days 59.21 ± 144.19 44.82 ± 72.46 0.811
 365 days 73.11 ± 233.46 13.23 ± 19.81 0.597
IFN-γ: pg/ml
 0 days 15.97 ± 35.87 3.49 ± 8.12
 60 days 7.04 ± 13.64 1.39 ± 2.33 0.264
 180 days 0.81 ± 0.84 0.84 ± 0.42 0.980
 365 days 4.58 ± 13.43 1.30 ± 0.97 0.544