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Table 2 Summary of Ross River virus experimental infection studies included in the review with description of methods and vertebrate species used

From: The non-human reservoirs of Ross River virus: a systematic review of the evidence

Reference Infection method Virus detection methods Vertebrate species tested (sample size) Virus co-infection
RRV strain Infection route Vector used
Boyd et al. [35] B94/20 Infected vector bite Yes Infection of a vector; magnitude and duration of viraemia (SMIC) Brushtail possum Trichosurus vulpecula (10) Simultaneous infection with Barmah Forest virus
Boyd & Kay [58] B94/20 Infected vector bite Yes Infection of a vector; magnitude and duration of viraemia (CCID50) Cat Felis catus (10); dog Canis lupus familiaris (10)  
Ryan et al. [33] B94/20 Infected vector bite Yes Infection of a vector; magnitude and duration of viraemia (TCID) Grey-headed flying fox Pteropus poliocephalus (10)  
Kay et al. [34] Not stated Intravenous injection and infected vector bite Yes Infection of a vector; magnitude and duration of viraemia (SMIC) Horse Equus ferus (11) Simultaneous infection with Murray Valley encephalitis
Kay et al. [27] Not stated Infected vector bite Yes Infection of a vector; magnitude and duration of viraemia (SMIC) Agile wallaby Macropus agilis (9); grey kangaroo Macropus giganteus (3); rabbit Oryctolagus cuniculus (9); sheep Ovis aries (8); pig Sus scrofa (11); horse Equus ferus (11); cattle Bos taurus (6); chicken Gallus gallus domesticus (20); black duck Anas rubripes (3); little corella Cacatua sanguinea (12) Simultaneous infection with Murray Valley encephalitis
Spradbrow [55] T48 Subcutaneous infection No Magnitude and duration of viraemia (LD50) Sheep Ovis aries (3); pig Sus scrofa domesticus (3)  
Whitehead [38] T48 Subcutaneous infection No Magnitude and duration of viraemia (LD50) Rabbit Oryctolagus cuniculus (4); rat Rattus spp. (4); bandicoot Isoodon macrourus (4); marsupial mouse Antechinus spp. (6); chicken Gallus gallus domesticus (16); pigeon Columba livia domestica (5) Simultaneous infection with Sindbis virus
  1. Abbreviations: SMIC, suckling mouse intracerebral injection; CCID50, cell culture infectious dose; TCID, tissue culture infectious dose; LD50, lethal dose per gm of whole blood