Fig. 5From: Bacillus subtilis spore with surface display of paramyosin from Clonorchis sinensis potentializes a promising oral vaccine candidateDetection of specific IgG and isotypes in sera from spore treated mice by ELISA assay. IgG levels in sera triggered by intraperitoneally (a) and intragastrically (c) immunized with recombinant spores. IgG1 and IgG2a levels in sera triggered by intraperitoneally (b) and intragastrically (d) immunized with recombinant spores. Data was expressed as the mean ± SD. Statistical significance was analyzed by the Student’s t-test (*P < 0.05, **P < 0.01, ***P < 0.001)Back to article page