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Table 2 Shared pfap2mu mutations observed in the isolates from the three sites. Mutations indicated in bold are known delayed clearance genotypes, underlined nucleotides are the changed bases

From: Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates

Nucleotide position

Nucleotide change

Amino acid position and change

446

CAG to CGG

Q149R

479

AGT to AAT

S160N

481

GTG to AAG

V161K

482

GTG to GAG

V161E

504

GAT to GAA

D168E

564

AGA to AGG

R188R

607

GAT to TAT

D203Y

607, 608

GAT to TTT

D203F

616

GAA to TAA

E206a

705

ACA to ACG

T235T

718

AAT to TAT

N240Y

767

AAG to TAG

K256a

789

GAT to GTT

D263V

810

GTA to GTT

V270V

852

GGA to GGG

G284G

855

AAG to GAG

K285E

951

AAC to AGC

N317S

954

ACA to ACC

T318T

  1. aStop codon