Reference | Study area, year of trial | Study design | Study population | Diagnosis | I1 | Malaria incidence/person months | I2 | Malaria incidence/ person months | I3 | Malaria incidence/ person months | I4 | Malaria incidence/ person months |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Beach et al., 1993 [35] | Kenya, 1990 | Quasi-experimental- with control group | Children < 6 years in 6 villages | Microscopy | ITNb | 82/195 | NIb | 136/193 | ITC | 170/224 | – | – |
Charlwood et al., 2001 [36] | Eastern Sudan, 1997 | Cluster RCT | All ages | PCR and microscopy | IRS | 46/418 | NI | 38/451 | – | – | – | – |
Cisse et al., 2006 [37] | Sahel and sub-Sahel region, 2002–03 | RCT | Children 2–59 months | Microscopy | PD | 39/1315 | NI | 222/1321 | – | – | – | – |
Dicko et al., 2011 [38] | Mali, 2008 | RCT | Children 3–59 months | Microscopy | PD | 149/4346 | NI | 832/4148 | – | – | – | – |
Fraser-Hurt, 1999 [39] | Tanzania, 1996 | RCT | Children 5–24 months | Microscopy | ITN | 173/360 | NI | 234/360 | – | – | – | – |
Hale, 2003 [40] | Ghana, 1998 | RCT | Adults | Microscopy | PD | 6/131 | NI | 86/117 | – | – | – | – |
Hamel, 2011 [41] | Kenya, 2000 | Quasi-experimental-control group | All ages > 6 months | RDT | IRS+ITN | 114/7424 | ITN | 251/6840 | – | – | – | – |
Hill et al., 2014 [62] | Yunnan, China, 2007 | RCT | All ages | Microscopy and RDT | ITN | 12/10,854 | NI | 73/10,857 | – | – | – | – |
Kamol-Ratanakul et al., 1992 [53] | Thailand, 1987–88 | RCT | Adults | Microscopy | ITN | 28/1026 | UN | 51/1099 | – | – | – | – |
Konate et al., 2011 [42] | Ghana, 2004 | RCT | Children < 6 years | Microscopy | ITN | 332/4564 | NI | 982/3504 | – | – | – | – |
Kroeger et al., 1995 [63] | South America, 1991–94 | Quasi-experimental-control group | All ages | Microscopy and RDT | ITN | 899/38,260 | NI | 1617/40,668 | – | – | – | – |
Kweku et al., 2008 [43] | Ghana, 2005–06 | RCT | Children 3–59 months | Microscopy | PD (monthly)b | 44/3756 | PD (bimonthly) | 112/3678 | PD (monthly) | 109/3372 | NIb | 183/3900 |
Luxemburger et al., 1994 [54] | Thailand-Burma, 1990–91 | RCT | School children 4–15 years | Microscopy | ITN | 29/933 | UN | 52/939 | – | – | – | – |
Lwin et al., 2012 [59] | Thailand, 2006–08 | RCT | Adults | Microscopy | PD | 5/2000 | NI | 69/845 | – | – | – | – |
Marbiah et al., 1998 [44] | Sierra Leone, 1992–93 | Cluster RCT | Children 3 months to 6 years | Microscopy | ITN | 48/590 | NI | 90/559 | – | – | – | – |
Mwangi et al., 2003 [45] | Kenya, 2000 | Quasi-experimental-control group | Children < 19 years | Microscopy | UNb | 62/638 | UNa | 22/42 | NIb | 58/383 | – | – |
Nankabirwa et al., 2014 [46] | Uganda, 2011–12 | RCT | Children 6–14 years | Microscopy | PD (monthly)b | 3/2886 | PD (school term) | 81/2857 | NIb | 83/2912 | – | – |
Nevill et al., 1988 [47] | Kenya, NR | RCT | Children 6–18 years | Microscopy | UNb | 1/130 | PDb | 8/123 | NI | 35/123 | – | – |
Odhiambo et al., 2010 [48] | Kenya, 2004–08 | RCT | Infants 5–16 weeks | Microscopy | PDe | 2/334 | PD | 2/334 | NIe | 17/325 | – | – |
Pinder et al., 2015 [49] | Gambia, 2010–11 | Cluster RCT | Children 6 months to 14 years | Microscopy and RDT | IRS | 15/886 | NI | 17/899 | – | – | – | – |
Rowland et al., 1996 [55] | Pakistan, 1991 | Quasi-experimental- control group | All ages | Microscopy | ITN | 235/8388 | NI | 541/8364 | – | – | – | – |
Sahu et al., 2003 [57] | India, 1999 | Cluster RCT | All ages | Microscopy | ITN | 3/551 | NI | 9/565 | – | – | – | – |
Sesay et al., 2011 [50] | Gambia, 2008 | RCT | Children < 5 years | Microscopy | PD | 1/2248 | NI | 3/2279 | – | – | – | – |
Sexton et al., 1990 [51] | Kenya, 1988 | RCT | All ages | Microscopy | ITNe | 55/339 | ITC | 34/323 | NIe | 75/322 | – | – |
Shah et al., 2013 [61] | India, 2006–11 | Quasi-experimental- control group | All ages | Microscopy | ITN | 124/34,272 | NI | 45/18,624 | – | – | – | – |
Sharma et al., 2009 [58] | India, 2006–07 | Cluster RCT | All ages | Microscopy | ITNe | 16/23,436 | UNb | 48/24,228 | NI | 50/12696 | – | – |
Smithuis et al., 2013 [32] | Myanmar, 1998 | Cluster RCT | Children < 10 years | Microscopy | ITN | 351/3989 | NI | 713/4053 | – | – | – | – |
Snow et al., 1988 [52] | Gambia, 1986 | Cluster RCT | Children 1–9 years | Microscopy | UN | 22/435 | NI | 20/303 | – | – | – | – |
Soleimani-Ahmad et al., 2012 [60] | Iran, 2009–10 | Cluster RCT | All ages | Microscopy | ITN | 17/7008 | NI | 35/7145 | – | – | – | – |
Taylor et al., 1999 [56] | Indonesia, 1996-97 | RCT | Adult (non-pregnant) 18–55 years | Microscopy | PDb | 28/467 | PD | 3/265 | NIe | 56/142 | – | – |