Spatio-temporal genetic structure of Anopheles gambiae in the Northwestern Lake Victoria Basin, Uganda: implications for genetic control trials in malaria endemic regions

Table 4 Geographical population structure indicated by F_ST. Mean of pairwise F_ST values reported by cited studies, unless noted

Contrast	Distance (km)	mtDNA nad5	Microsatellites	SNP/SNP Array
Mainland	5–100	0.017 [37]	0.0039^a–0.013^b	–
	200–800	0.032 [37]	0.0064^a–0.031^b	–
	1000–7000	0.085 [37]	0.0161^a–0.039^b	0.023^g
Main-Oceanic	50–100	–	0.0238^c	0–0.016^h
	300–400	–	0.050^d	–
	600–800	–	–	0.20–0.25^h
Main-Lacustrine	2–20	–	0.003^e	–
Main-Lacustrine	25–100	0.059–0.077	0.070^f (0.062)	–

^aAverage across 9 loci from [16], only comparisons within NW and SE subdivisions for An. gambiae (S-form)
^bAverage across 13 chromosome-3 loci from [17], only comparisons within An. gambiae (S-form) excluding Mozambique
^cAverage across 8 chromosome-3 loci from [19], only comparison within An. gambiae (S-form) between Tiko (mainland) and island site
^dAverage across 11 chromosome-3 loci from [21], only comparison within An. gambiae (S-form) between Libreville (mainland) and island site
^eGlobal F_ST for 6 loci between 7 island and 6 mainland villages, from [24]
^fAverage across 17 loci from [25], only comparisons between island versus mainland sites; smaller value in parenthesis is average across 13 loci after removal of 4 in neighborhood of inversions (Table 6 of [25])
^gBased on whole genome sequences from [9], comparisons limited to An. gambiae (S-form) excluding Kenya
^hBased on 52- and 31-SNP arrays from [20]

ISSN: 1756-3305