Skip to main content
Fig. 4 | Parasites & Vectors

Fig. 4

From: The Toxoplasma gondii ME-49 strain upregulates levels of A20 that inhibit NF-κB activation and promotes apoptosis in human leukaemia T-cell lines

Fig. 4

The apoptosis effects induced by T. gondii ME-49 after ABIN1 knockdown and over-expression of ABIN1 and effects of T. gondii ME-49 on the Cleaved-Casp8 (p43/p41) expression levels. a, b The Cleaved-Casp8 (p43/p41) protein levels in Jurkat T-cells and Molt-4 T-cells infected with T. gondii ME-49 (5 × 106 cells/ml) after ABIN1 knockdown and over-expression of ABIN1. c, d Western blot analysis of knockdown efficiency of lentivirus and over-expression plasmid in Jurkat T-cells and Molt-4 T-cells. e, f The apoptosis rate in Jurkat T-cells and Molt-4 T-cells infected with T. gondii ME-49 (5 × 106 cells/ml) after ABIN1 knockdown and over-expression of ABIN1. Values are represented as the mean ± SD (n = 3). *P < 0.05 vs the control group; **P < 0.01 vs the control group; #P < 0.05 vs the ME-49 group

Back to article page