Parasites & Vectors

Table 2 Molluscicidal activity and egg hatchability inhibitory activity of compounds 8 and 9

From: Discovery of the pyridylphenylureas as novel molluscicides against the invasive snail Biomphalaria straminea, intermediate host of Schistosoma mansoni

Compound	Adult snails				Egg hatchability
Compound	LC₅₀ (mg/l)^a	LC₉₀ (mg/l)^a	χ ^2b	P ^b	IC₅₀ (mg/l)^a	IC₉₀ (mg/l)^a	χ ^2b	P ^b
8	0.50 (0.44–0.57)	0.98 (0.82–1.25)	4.14	0.25	0.05 (0.038–0.056)	0.21 (0.19–0.25)	1.88	0.39
9	0.51 (0.46–0.57)	0.78 (0.69–0.97)	3.84	0.43	0.09 (0.081–0.111)	0.39 (0.35–0.44)	2.88	0.41
Niclosamide	0.114^c/0.049^d	0.212^c/0.063^d	–	–	0.01 (0.009–0.016)	0.06 (0.047–0.085)	1.18	0.56

^aValues are given as means with 95% confidence intervals in parentheses
^bPearson chi-square goodness-of-fit test
^c[31]
^d[34]

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