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Table 2 Molluscicidal activity and egg hatchability inhibitory activity of compounds 8 and 9

From: Discovery of the pyridylphenylureas as novel molluscicides against the invasive snail Biomphalaria straminea, intermediate host of Schistosoma mansoni

Compound Adult snails Egg hatchability
LC50 (mg/l)a LC90 (mg/l)a χ 2b P b IC50 (mg/l)a IC90 (mg/l)a χ 2b P b
8 0.50 (0.44–0.57) 0.98 (0.82–1.25) 4.14 0.25 0.05 (0.038–0.056) 0.21 (0.19–0.25) 1.88 0.39
9 0.51 (0.46–0.57) 0.78 (0.69–0.97) 3.84 0.43 0.09 (0.081–0.111) 0.39 (0.35–0.44) 2.88 0.41
Niclosamide 0.114c/0.049d 0.212c/0.063d – – 0.01 (0.009–0.016) 0.06 (0.047–0.085) 1.18 0.56
  1. aValues are given as means with 95% confidence intervals in parentheses
  2. bPearson chi-square goodness-of-fit test
  3. c[31]
  4. d[34]
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Parasites & Vectors

ISSN: 1756-3305

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