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Table 1 Flea-control efficacy fluralaner-treated dogs compared to sham-treated controls in a simulated home environment

From: A single topical fluralaner application to cats and to dogs controls fleas for 12 weeks in a simulated home environment

Days pre/post-treatment Mean flea count (arithmetic/geometric) % Efficacy (arithmetic/geometric) t ( df) P
Control groupa Fluralaner groupa
-1 41.6/24.2 (10/10) 19.4/10.4 (8/10) na   
1 4.4/2.9 (8/10) *0.2/0.1 (1/10) 95.5/96.0 t(9.0) = -4.198 0.002
7 5.2/4.0 (10/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -7.425 < 0.0001
14 4.0/2.5 (9/10) **0.3/0.1 (1/10) 92.5/94.1 t(18.0) = -3.740 0.001
21 26.7/12.6 (8/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -4.947 0.001
28 27.8/19.9 (10/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -9.925 < 0.0001
35 31.8/30.3 (10/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -33.26 < 0.0001
42 17.7/15.0 (10/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -15.80 < 0.0001
49 34.8/32.8 (10/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -30.95 < 0.0001
56 47.5/40.2 (10/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -18.43 < 0.0001
63 21.9/15.4 (10/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -10.72 < 0.0001
70 12.3/8.9 (10/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -10.49 < 0.0001
77 40.4/37.7 (10/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -32.10 < 0.0001
84 58.0/52.8 (10/10) **0.0/0.0 (0/10) 100/100 t(9.0) = -28.25 < 0.0001
  1. Abbreviations: df degrees of freedom, na not applicable (pre-treatment)
  2. aNumber infested/total number in group
  3. Significantly different from control group: *P = 0.002, **P ≤ 0.001