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Table 2 Flea-control efficacy fluralaner-treated cats compared to sham-treated controls in a simulated home environment

From: A single topical fluralaner application to cats and to dogs controls fleas for 12 weeks in a simulated home environment

Days pre/post-treatment

Mean flea count (arithmetic/geometric)

% Efficacy (arithmetic/geometric)

t ( df)

P

Control groupa

Fluralaner groupa

-1

18.4/15.9 (9/9)

25.9/10.6 (9/10)

na

1

2.9/1.9 (6/9)

*0.1/0.1 (1/10)

96.5/96.1

t(9.2) = -3.447

0.007

7

0.7/0.4 (3/9)

0.0/0.0 (0/10)

na

14

0.8/0.4 (3/9)

0.0/0.0 (0/10)

na

21

17.1/12.1 (8/9)

**0.0/0.0 (0/10)

100/100

t(8.7) = -7.603

< 0.0001

28

36.6/33.3 (9/9)

**0.0/0.0 (0/10)

100/100

t(8.7) = -24.84

< 0.0001

35

19.2/17.1 (9/9)

**0.0/0.0 (0/10)

100/100

t(9.0) = -17.77

< 0.0001

42

12.2/9.9 (9/9)

**0.0/0.0 (0/10)

100/100

t(9.0) = -11.31

< 0.0001

49

11.0/10.0 (9/9)

**0.0/0.0 (0/10)

100/100

t(8.7) = -16.51

< 0.0001

56

23.1/21.5 (9/9)

**0.0/0.0 (0/10)

100/100

t(8.7) = -24.77

< 0.0001

63

16.8/15.4 (9/9))

**0.0/0.0 (0/10)

100/100

t(8.7) = -20.99

< 0.0001

70

16.4/12.9 (9/9)

**0.0/0.0 (0/10)

100/100

t(8.7) = -11.24

< 0.0001

77

17.7/14.9 (9/9)

**0.0/0.0 (0/10)

100/100

t(8.7) = -14.94

< 0.0001

84

37.0/32.7 (9/9)

**0.0/0.0 (0/10)

100/100

t(8.7) = -24.18

< 0.0001

  1. Abbreviations: df degrees of freedom, na not applicable pre-treatment or < 6 control cats were infested and efficacy not calculated
  2. aNumber infested/total number in group
  3. Significantly different from control group: *P = 0.007, **P ≤ 0.001