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Table 2 Flea-control efficacy fluralaner-treated cats compared to sham-treated controls in a simulated home environment

From: A single topical fluralaner application to cats and to dogs controls fleas for 12 weeks in a simulated home environment

Days pre/post-treatment Mean flea count (arithmetic/geometric) % Efficacy (arithmetic/geometric) t ( df) P
Control groupa Fluralaner groupa
-1 18.4/15.9 (9/9) 25.9/10.6 (9/10) na
1 2.9/1.9 (6/9) *0.1/0.1 (1/10) 96.5/96.1 t(9.2) = -3.447 0.007
7 0.7/0.4 (3/9) 0.0/0.0 (0/10) na
14 0.8/0.4 (3/9) 0.0/0.0 (0/10) na
21 17.1/12.1 (8/9) **0.0/0.0 (0/10) 100/100 t(8.7) = -7.603 < 0.0001
28 36.6/33.3 (9/9) **0.0/0.0 (0/10) 100/100 t(8.7) = -24.84 < 0.0001
35 19.2/17.1 (9/9) **0.0/0.0 (0/10) 100/100 t(9.0) = -17.77 < 0.0001
42 12.2/9.9 (9/9) **0.0/0.0 (0/10) 100/100 t(9.0) = -11.31 < 0.0001
49 11.0/10.0 (9/9) **0.0/0.0 (0/10) 100/100 t(8.7) = -16.51 < 0.0001
56 23.1/21.5 (9/9) **0.0/0.0 (0/10) 100/100 t(8.7) = -24.77 < 0.0001
63 16.8/15.4 (9/9)) **0.0/0.0 (0/10) 100/100 t(8.7) = -20.99 < 0.0001
70 16.4/12.9 (9/9) **0.0/0.0 (0/10) 100/100 t(8.7) = -11.24 < 0.0001
77 17.7/14.9 (9/9) **0.0/0.0 (0/10) 100/100 t(8.7) = -14.94 < 0.0001
84 37.0/32.7 (9/9) **0.0/0.0 (0/10) 100/100 t(8.7) = -24.18 < 0.0001
  1. Abbreviations: df degrees of freedom, na not applicable pre-treatment or < 6 control cats were infested and efficacy not calculated
  2. aNumber infested/total number in group
  3. Significantly different from control group: *P = 0.007, **P ≤ 0.001