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Table 2 Antigens that showed significant IgG response at day 40 in mice infected with oocysts

From: Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts

Rank a

Gene ID_exon

Description

Benjamini-Hochberg corrected P-value (d0 vs d40)

1

TGME49_070240_3

Unspecified product (MAG1)

P < 0.0001

2

TGME49_003310_1

Dense granule protein GRA7

P < 0.0001

3

TGME49_075440_1

Granule antigen protein GRA6

P < 0.0001

4

TGME49_054720_1

Dense granule protein GRA8

P < 0.0001

5

TGME49_086450_1

Dense granule protein 5 precursor

P < 0.0001

6

TGME49_109590_1

Rhoptry protein 1

P < 0.0001

7

TGME49_110780_1

Dense granule protein GRA4

P < 0.0001

8

TGME49_021710_4

TBC domain-containing protein

P = 0.0014

9

TGME49_039740_1

Dense granule protein GRA14

P < 0.0001

10

TGME49_027280_1

Dense granule protein GRA3

P < 0.0001

11

TGME49_001780_2

Microneme protein MIC2

P = 0.0003

12

TGME49_027620_2

Dense granule protein GRA2

P < 0.0001

13

TGME49_004050_8

Subtilisin SUB1

P = 0.0007

14

TGME49_033450_1

SAG-related sequence SRS29A

P = 0.0151

15

TGME49_091890_4

Microneme protein MIC1

P = 0.0003

16

TGME49_026380_1

Hypothetical protein

P = 0.0429

17

TGME49_067680_8

Microneme protein MIC12

P = 0.0151

18

TGME49_109750_1

Succinate-Coenzyme A ligase, beta subunit

P = 0.0275

19

TGME49_087480_7

Hypothetical protein

P = 0.0483

20

TGME49_022370_1

SAG-related sequence SRS13

P = 0.0445

21

TGME49_042320_16

B-box zinc finger domain-containing protein

P = 0.0190

22

TGME49_026510_1

Sec23/Sec24 trunk domain-containing protein

P = 0.0359

23

TGME49_039540_2

LEM3 (ligand-effect modulator 3) family

P = 0.0280

24

TGME49_033480_1

SAG-related sequence SRS29C

P = 0.0358

25

TGME49_051630_2

Slc30a2 protein

P = 0.0361

26

TGME49_015980_1

Hypothetical protein

P = 0.0358

27

TGME49_054570_14

Hypothetical protein

P = 0.0483

28

TGME49_088960_2Seg3

Hypothetical protein

P = 0.0358

29

TGME49_058660_2

Rhoptry protein ROP6

P = 0.0358

30

TGME49_045510_2

Phospholipid-translocating P-type ATPase

P = 0.0483

31

TGME49_033530_1

Hypothetical protein

P = 0.0364

32

TGME49_088380_4

Heat shock protein HSP90

P = 0.0430

33

TGME49_118460_1

P-type ATPase

P = 0.0430

34

TGME49_043730_1

Rhoptry protein ROP9

P = 0.0364

35

TGME49_048770_6

Hypothetical protein

P = 0.0430

36

TGME49_089520_5

Hypothetical protein

P = 0.0498

37

TGME49_017740_2

3-ketoacyl-(acyl-carrier-protein) reductase

P = 0.0483

38

TGME49_104460_1

Zinc finger, C3HC4 type (RING finger) domain-containing protein

P = 0.0483

39

TGME49_016630_7

Trigger factor protein, putative

P = 0.0498

40

TGME49_092050_3

Calcium dependent protein kinase CDPK8

P = 0.0483

  1. aBased on average signal value, as per Figs. 3 and 4