Skip to main content

Advertisement

Table 2 Antigens that showed significant IgG response at day 40 in mice infected with oocysts

From: Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts

Rank a Gene ID_exon Description Benjamini-Hochberg corrected P-value (d0 vs d40)
1 TGME49_070240_3 Unspecified product (MAG1) P < 0.0001
2 TGME49_003310_1 Dense granule protein GRA7 P < 0.0001
3 TGME49_075440_1 Granule antigen protein GRA6 P < 0.0001
4 TGME49_054720_1 Dense granule protein GRA8 P < 0.0001
5 TGME49_086450_1 Dense granule protein 5 precursor P < 0.0001
6 TGME49_109590_1 Rhoptry protein 1 P < 0.0001
7 TGME49_110780_1 Dense granule protein GRA4 P < 0.0001
8 TGME49_021710_4 TBC domain-containing protein P = 0.0014
9 TGME49_039740_1 Dense granule protein GRA14 P < 0.0001
10 TGME49_027280_1 Dense granule protein GRA3 P < 0.0001
11 TGME49_001780_2 Microneme protein MIC2 P = 0.0003
12 TGME49_027620_2 Dense granule protein GRA2 P < 0.0001
13 TGME49_004050_8 Subtilisin SUB1 P = 0.0007
14 TGME49_033450_1 SAG-related sequence SRS29A P = 0.0151
15 TGME49_091890_4 Microneme protein MIC1 P = 0.0003
16 TGME49_026380_1 Hypothetical protein P = 0.0429
17 TGME49_067680_8 Microneme protein MIC12 P = 0.0151
18 TGME49_109750_1 Succinate-Coenzyme A ligase, beta subunit P = 0.0275
19 TGME49_087480_7 Hypothetical protein P = 0.0483
20 TGME49_022370_1 SAG-related sequence SRS13 P = 0.0445
21 TGME49_042320_16 B-box zinc finger domain-containing protein P = 0.0190
22 TGME49_026510_1 Sec23/Sec24 trunk domain-containing protein P = 0.0359
23 TGME49_039540_2 LEM3 (ligand-effect modulator 3) family P = 0.0280
24 TGME49_033480_1 SAG-related sequence SRS29C P = 0.0358
25 TGME49_051630_2 Slc30a2 protein P = 0.0361
26 TGME49_015980_1 Hypothetical protein P = 0.0358
27 TGME49_054570_14 Hypothetical protein P = 0.0483
28 TGME49_088960_2Seg3 Hypothetical protein P = 0.0358
29 TGME49_058660_2 Rhoptry protein ROP6 P = 0.0358
30 TGME49_045510_2 Phospholipid-translocating P-type ATPase P = 0.0483
31 TGME49_033530_1 Hypothetical protein P = 0.0364
32 TGME49_088380_4 Heat shock protein HSP90 P = 0.0430
33 TGME49_118460_1 P-type ATPase P = 0.0430
34 TGME49_043730_1 Rhoptry protein ROP9 P = 0.0364
35 TGME49_048770_6 Hypothetical protein P = 0.0430
36 TGME49_089520_5 Hypothetical protein P = 0.0498
37 TGME49_017740_2 3-ketoacyl-(acyl-carrier-protein) reductase P = 0.0483
38 TGME49_104460_1 Zinc finger, C3HC4 type (RING finger) domain-containing protein P = 0.0483
39 TGME49_016630_7 Trigger factor protein, putative P = 0.0498
40 TGME49_092050_3 Calcium dependent protein kinase CDPK8 P = 0.0483
  1. aBased on average signal value, as per Figs. 3 and 4